Reel Adventure Seeds

Inspiration is where you find it. 

Here are a few adventure seeds, side quests--what have you--riffed off of films which might not neccessarily scream "adventure fodder."  Throw 'em in your sandbox and see what your player's do with 'em.

Mild SPOILERS follow, if you haven't seen the films. 

"What happened to her eyes?"

Quarantined by fearful authorities in a sprawling but isolated keep, the players combat an outbreak of a strange contagion which turns its victims into raving undead.

"Men like tempered steel.  Tough breed.  Men who learn to endure."

The PCs are hired by a nobleman to rescue his wife who has supposedly been kidnapped by a half-orc bandit chieftain, and taken to his wilderness stronghold.  As the mission unfolds, the PCs find that everything may not be as simple as they've been told.

"Ghost or not, I'll split you in two."

In a rural fiefdom, people live in fear of a monster which strikes without warning, killing people and livestock.  The PCs are hired to find the mysterious beast.  The hunt isn't easy as it appears, as powerful conspiracies fester, and the monster attacks may only be part of a larger, sinister plan.

"There ain't nothing sacred about a hole in the ground or the man that's in it.  Or you. Or me."

The PCs hear that a nobleman is offering a hefty reward for anyone who brings him the head of the scoundrel who got his daughter with child.  A little investigation reveals the scoundrel is already dead and buried, which ought to make acquiring his head easy...Except that the grave's in hostile territory and other bounty-hunters are on the trail.

"ribbit."

A PC excitedly brings an old box he found in the corner of a dungeon to the rest of the party.  It contains an ordinary appearing frog.  The PC relates that the frog told him that it's actually a Slaad potentate imprisoned on this plane, and cursed to this form.  If the PCs aid its return to its home plane, it promises them vast riches as reward.  This is what the frog's discoverer assures the others.  The frog or Slaad, however, never speaks to anyone but the character who found it...